FA Cup holders Leicester will host Huddersfield in the fifth round if they get past Nottingham Forest on Sunday.
The Foxes beat Chelsea in last season's final and will fancy their chances of reaching the quarter finals if they can get past their local rivals.
Elsewhere, Chelsea have been drawn away at Luton, while Boreham Wood could visit Everton if the lowest ranked team in the competition can squeeze past Bournemouth.
Manchester City will visit Peterborough, Norwich will travel to either Liverpool or Cardiff, Middlesbrough will host Tottenham and Southampton will take on West Ham at St Mary's in the only confirmed all Premier League clash so far.
FA Cup fifth round draw
Luton vs Chelsea
Peterborough vs Manchester City
Liverpool or Cardiff vs Norwich
Southampton vs West Ham
Middlesbrough vs Tottenham
Nottingham Forest or Leicester vs Huddersfield
Everton vs Bournemouth or Boreham Wood
FA Cup fifth round dates
This year the ties for the FA Cup fifth round are taking place in midweek. The FA website record the date for the ties as Wednesday 2 March, but it is likely that fixtures will take place on the Tuesday and Thursday of that week too.