Victor Moses and James McCarthy are back training for Wigan but are unlikely to return for the trip to Arsenal.
Moses (shoulder) and McCarthy (ankle) have been long-term casualties at the DW Stadium but could now return for next weekend's FA Cup clash with Bolton.
Franco Di Santo made a substitute appearance against Fulham last weekend after an ankle injury and could play a part at the Emirates.
Chris Kirkland was unavailable for the Fulham game after a head injury and it remains to be seen if he will start ahead of Ali Al Habsi while Tom Cleverley (hamstring) is out.
Source: PA