Wycombe suffered relegation from League One at the end of last season after only going up the previous year.
The Minstermen then have successive away trips to Morecambe and Barnet over the next seven days before entertaining both Oxford United and Chesterfield.
The Christmas programme includes a visit to the Spireites on Boxing Day and the arrival of Burton Albion to Bootham Crescent on New Year's Day.
The regular season is due to end at Dagenham & Redbridge in late April.
Fixtures 2012-13
Source: FOOTYMAD