Fortunately Birmingham, Reading, Cardiff all lost as well this weekend, meaning Wolves still hold a three-point lead at the summit, but McCarthy wants his players to put all of that out of their mind ahead of the trip to Selhurst Park.
"Forget any any pressure, where's the pressure? Let's just go and play," he told the club's official website. "There haven't been any demands on the players to do anything differently, let's just go and play.
"Palace is no easy place to play but we've got to go there and do it. It might be good to have another game so soon, let's get them played.
"Tuesday-Saturday-Tuesday-Saturday - whatever comes now we've just got to be ready for them and play better than we did on Saturday."