Having lost their last two Premier League games against Sunderland and Portsmouth, McCarthy knows his side have to hit the ground running at Goodison Park to get their season back on track.
He said: "I hope that there is a difference this time. But how can I prevent what happened then? There is no easy way around it.
"After the first 18 minutes at Blackburn it was less than good. I have got to say that it was really poor.
"We didn't start badly in the game but as soon as they scored everything changed about the team.
"Not giving the ball away to give away the first goal would be a help. Let's not do that and let's mark at corners.
"I'd have liked to have had all of the players here for two weeks, but they weren't so there's no point whinging about it and we just have to get on with things.
"The frustration of it is that we won't see them as a whole group until Friday and that does makes things difficult but it affects the other teams as well."
McCarthy had Wayne Hennessey, Christophe, Berra, Kevin Foley, Andy Keogh, Kevin Doyle, David Edwards, Nenad Milijas, Stefan Maierhofer and Segundo Castillo away with their countries.
Former Republic of Ireland boss McCarthy thinks that changing when the international games are played would help club managers.
He would prefer to see the first international played on a Wednesday or a Thursday and the second on the following Saturday or Sunday to give the players more time back at their clubs.
McCarthy said: "Perhaps you should play Wednesday and Saturday or even Wednesday, Sunday. It is really for us to discuss, but it would make things a lot easier for the clubs.
"However, I can see things both sides because I have been an international manager.
"But I have got Segundo flying in from South America and he is going to be feeling terrible when he gets back after 12 hours on a plane.
We will just have to wait and see how he feels before we can decide whether he will play at Everton."
McCarthy is set to make changes to his side for the trip to Goodison Park.
Winger Michael Kightly and striker Sylvan Ebanks-Blake are both pushing to return to the starting line-up after injury problems.
Kightly has not started a first-team game since March following hip and foot problems.
But he is now fully match fit, as is Ebanks-Blake whose last start was on the opening day of the season against West Ham United when he suffered a hamstring strain.
Everton 4/9, Draw 3/1, Wolves 15/2