Ireland face the Super Eagles at Fulham's Craven Cottage and Foley is one of two Wolves players in the squad alongside Andrew Keogh, who is expected to start on the bench.
Foley, fans' player of the season at Molineux, has appeared as an unused substitute for his country on several occasions, but will be rewarded for an impressive season in which he started all but one of his club's 46 Championship games.
The right-back is one of five debutants in Trapattoni's experimental line-up. Preston defenders Sean St Ledger and Eddie Nolan, Stoke midfielder Liam Lawrence and Coventry striker Leon Best are the other uncapped players named.
Former Wolves players Robbie Keane and Keith Andrews will both start alongside Foley.