Wigan pair Hugo Rodallega and Antolin Alcaraz are suspended for the Barclays Premier League clash at West Ham.
Both players were sent off at Manchester United last week and must serve three and one-match bans respectively.
Defender Gary Caldwell has an outside chance of returning from a thigh injury while on-loan Tom Cleverley is back after missing the game against parent club United.
Emmerson Boyce (hamstring) and James McCarthy (ankle) remain on the sidelines. Veteran goalkeeper Mike Pollitt will be on the bench following Chris Kirkland's loan move to Leicester.