Wigan boss Roberto Martinez admits his team have a mental block when it comes to playing Manchester United.
The relegation-threatened Latics have not taken a point from the current Barclays Premier League leaders since they were promoted to the top flight in 2005.
Their need to break that hoodoo is more urgent than ever as United visit the DW Stadium on Saturday at the start of a tough run of fixtures for Martinez's side.
Wigan next face Manchester City before taking on relegation rivals Birmingham and two more Champions League contenders in Tottenham and Chelsea.
Martinez said: "We are not just facing the league leaders, which is a fantastic challenge, but through our history we have never taken one point from Manchester United. It is a mental block.
"But last year was the first time we beat any of the 'top four' teams, and we beat three of them. Manchester United are the only ones we have never taken anything from in the last six years. It makes it an important challenge."