Wigan boss Roberto Martinez admitted "it was a tough night" after his side lost 2-0 at Arsenal in the quarter-finals of the Carling Cup.
The Gunners missed several good chances before they took the lead on the stroke of half-time through an own goal from Latics skipper Antolin Alcaraz with Nicklas Bendtner's close-range effort after 67 minutes securing the win.
To add to Wigan`s disappointment, striker Mauro Boselli limped off with a knee problem while Victor Moses could be out for up to six weeks with a suspected dislocated shoulder.
"It has been a great competition for us but it was probably a game too many," Martinez said. "There were a couple of performances from players like James McArthur, Ben Watson and youngster Callum McManaman, which were positive, but it was a tough night."
Martinez, though, insisted his squad would bounce back as they battle for Barclays Premier League survival.
"Sometimes you need to earn your own luck and I don't want us to be a team which feels sorry for ourselves," he added. "Now is one of the key moments, we need to regroup and act like men. We are short in numbers, but not in character. It would be very easy to feel sorry for ourselves, but if we carry on working with levels have been showing, luck can change very quickly."