Wigan boss Owen Coyle expects a 'special' night on Thursday as the DW Stadium hosts European football for the first time.
Slovenian side Maribor are the visitors as the FA Cup winners go in search of a first victory in continental competition following their goalless draw against Zulte Waregem a fortnight ago.
Maribor have never beaten an English side but they have a lot more experience at this level than Wigan and lost out to Victoria Plzen in the final round of qualifying for the Champions League group stages.
The Slovenians lost 5-2 to Rubin Kazan in their first Europa League match and sacked manager Ante Cacic on Sunday, with Ante Simundza stepping in to take charge in time for Thursday's game.
Coyle said: "It's the first home tie. We've obviously had the experience of the first European tie for the club against Zulte Waregem in Belgium, where we acquitted ourselves very well.
"And what we want to do now is achieve maximum points tomorrow night, which would put us in a nice place in terms of the standings in the group.
"But to do that we're going to have to play very well because they're a very good side. They changed their coach at the weekend so that brings one or two things that they may change.
"For us, it's important we get to our standard and perform as we can. We've got good players and we're in the process of building a very good team.
"Nothing's altered our opinion that we're set for a very successful and exciting season, and tomorrow night provides that as well.
"Hopefully it will be a special atmosphere. Coming along for the first home European tie, it will be a special night for everybody."