West Brom boss Bryan Robson has left the club by mutual consent following Albion's mixed start to the season.
The Baggies are ninth in the Championship table following last season's relegation and fans called for Robson to be sacked after Saturday's disappointing 1-1 draw with Southend United at The Hawthorns.
Chairman Jeremy Peace told the club's official website: "After much deliberation, and in view of the results since early 2006, it has been decided that a change is necessary if the club is to achieve its aims for this season and beyond.
"This is a very important time for West Bromwich Albion. With promotion a priority, the board felt that given the club's current league position, the best way forward was to agree to make a change now."
Former England captain Robson was appointed Albion manager in November 2004 following Gary Megson's departure and helped the club avoid relegation from the Premiership on the last day of the 2004-05 season.
However, the former Middlesbrough and Bradford City boss was unable to stop Albion being relegated last term and guided the club to only three wins in their opening nine Championship matches of this season.
Nigel Pearson has been placed in control of first-team affairs.