The veteran midfielder is suspended after picking up his fifth booking of the season at the weekend and his place goes to Anderson, who impressed as a second-half substitute against QPR. Antonio Valencia (hip) has an outside chance of being fit for the leaders, but fellow winger Nani remains sidelined with a hamstring problem. Chris Smalling and Phil Jones are available after being unused substitutes against QPR, while David de Gea was also on the bench for the 3-1 win after a recent problem with his wisdom teeth. Midfielder Mark Noble is suspended for West Ham's trip to Old Trafford after accumulating five yellow cards. Left-back George McCartney is a doubt after suffering an ankle injury against Tottenham and midfielder Yossi Benayoun is still not available as he looks to overcome a thigh problem. Midfielder Jack Collison (knee) and forward Ricardo Vaz Te (shoulder) are also ruled out.