Noble has proved a quick-healer in the past and hopes to defy the forecast after picking up the injury near the end of the defeat at Liverpool.
Scott Parker and Valon Behrami, missing at Anfield, trained on Thursday and hope to be back for Saturday's game against fellow-strugglers Wigan, which the club have dramatically billed as a 'Save Our Season' clash.
Missing man: Noble faces at least a month on the sidelines after his leg injury fears were confirmed
Avram Grant and his players have been left in no doubt about the seriousness of their predicament, a feeling enhanced when vice-chairman Karren Brady descended upon the training ground this week.
It was the first in her 17 years in football that Brady had felt the need to visit the players' training base.
Upton Park is expected to be full on Saturday after ticket prices were slashed to £20 in an effort to generate noisy support for a team with only one Barclays Premier League win this season.
Welcome back: West ham are boosted by the return of influential midfielder Parker to face Wigan
Manager Grant is already feeling the heat after his unpopular assistant Zeljko Petrovic was fired this week and replaced by Wally Downes.
West Ham hero Paolo Di Canio, who has recently passed his coaching qualifications in Italy and is searching for a job in England, will also be at Upton Park on Saturday in the executive suite named in his honour.
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