Following scans Bent has been instructed to wear a knee brace for a fortnight before specialists make a further assessment.
Related ArticlesKing: I want to play in the World CupRef apologises to RedknappBastos tipped for Spurs moveAlmunia: England's No 1Owen still has England chanceSpurs revive interest in Roque Santa CruzBent will definitely miss the visit of bottom club West Bromwich Albion and next weekend's trip to Everton.
Manager Harry Redknapp is now hoping Roman Pavlyuchenko, who has missed the last two games with a back injury, can return.
The Russian has not started a game since early March but scored in his last appearances, as a substitute, at home to West Ham.
But if both strikers are ruled out he will give Jermain Defoe his first start since January, after the England striker recovered from a foot injury.
Meanwhile, Ledley King has spoken for the first time about his England future and has confirmed that he wants to be a part of Fabio Capello's World Cup squad.
The Tottenham captain earned a surprise call-up for England's friendly against Slovakia and the World Cup qualifier against Ukraine, only to withdraw with his troublesome knee problem.
"It's a difficult situation," said King.
"My priority first and foremost is always Spurs, but of course every player wants to represent his country at the highest level and, with the 2010 World Cup qualifying campaign going so well, there is a real opportunity to do something great on the international stage again.