The 30-year-old has been bedevilled by injuries in recent years, particularly to his knees, undertaking a limited training programme in order to manage the problem.
Crocks your lot: Ledley King's career has been badly hampered by injury
The news comes as a blow to Redknapp, who is already without the suspended Michael Dawson and injured Younes Kaboul and William Gallas at the back. However Jonathan Woodgate is fit again for the first time since November 2009, but Redknapp admitted throwing the former Real Madrid man straight back into action was far from idea.
Redknapp said: 'Ledley will have an operation. He is nowhere near ready to play.'
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Explore more:People: Jonathan Woodgate, William Gallas, Michael Dawson, Ledley King, Harry Redknapp, Younes Kaboul