Victory would not guarantee a place in the Europa Cup but would put pressure on Fulham to get at least a point against Everton at Craven Cottage.
The Brazilian said: "We can win at Liverpool. We have confidence for this game and we will give everything we have for one last time this season.
"Teams like Liverpool will always play well, but they do give you space to play, so we can definitely score. Hopefully we can keep another clean sheet as well.
"We will look to improve on our away form next season, because if we picked up more points on the road, we would be fighting even higher up the table."
Spurs broke an 89-year record by conceding just 10 goals at White Hart Lane, and Gomes added: "It's a brilliant achievement for the whole team and we worked very hard for it.
"Defending starts from the front and all the lads have played very well, especially at home - we make it very difficult for teams to come to the Lane."
Meanwhile, Spurs' players have this week taken part in Soccer AM's Crossbar Challenge.
The Crossbar Challenge involves players attempting to hit the crossbar from the halfway line of a full size pitch, and their attempts will be shown on the Sky Sports 1 programme on Saturday morning.