Phil Neville is among those currently working their way back to full fitness, with the vastly-experienced club captain continuing with his recovery from knee surgery.
Kevin Mirallas (hamstring) has been out of action for a month, and remains sidelined for the weekend, while Victor Anichebe (hamstring) is also no nearer to pushing for a recall after seven weeks on the treatment table.
Tottenham defender Michael Dawson has only a slim chance of recovering from his hamstring injury in time to make the trip to Merseyside.
Winger Gareth Bale is out with hamstring problem of his own, while Hugo Lloris is expected to replace Brad Friedel between the sticks after the American started Thursday night's Europa League win over Panathinaikos.
Midfielder Scott Parker (Achilles) and left-back Benoit Assou-Ekotto (knee) are a week away from full fitness and defender Younes Kaboul (knee) is also unavailable.