Spurs have been in the spotlight following Ledley King's recent arrest, with Defoe then attracting media attention at a recent outing in London.
The 26-year-old insists he is teetotal and spoke to defend his team-mates after increased criticism from some quarters.
Insisting his playing career is too important to him to risk, Defoe said: "Especially coming back from injury, you have to be professional.
Reaction"If you think about it, if I was one of those people drinking every week I don't think I'll be able to perform how I perform."
Reacting to recent photographs of him pictured after helping judge the Miss World competition in London, Defoe said: "I wasn't happy.
"It's crazy when you pick up the papers and you read something that is so far from the truth, like you're in a nightclub 48 hours before a game.
"The thing is I've never had a problem. In the time I've been playing football there has never been anything about me drinking.
"I don't see why all of a sudden people say I'm drinking," he added. "It's unbelievable. I went to an event on Tuesday , then I was with my family and I went home. We had a day off on Wednesday and I performed on Saturday."
Hitting back at suggestions that Spurs is a club of drinkers, Defoe said: "It's so far from the truth.
"It's difficult for the boys when you pick up the papers and read things. Most of the time people believe what they read.
"It's unbelievable because we have a great bunch of lads and everyone is so professional."