A Metropolitan Police spokesman said: "London Ambulance Service (LAS), Hems (helicopter emergency medical service) and police attended and discovered the 36-year-old male motorcyclist suffering from injuries described by LAS as possibly life-changing.
Related ArticlesPavlyuchenko desperate to leave SpursSpurs spend more than 'Big Four'Crouch puts his best foot forwardTottenham record record profitsRedknapp wants Muntari reunion"He has been taken to an east London hospital for further assessment and treatment."
The woman driver of the car and a child who was in the car with her did not need hospital treatment.
Roads were closed in the area after the incident which is being investigated by the Chadwell Heath collision investigation unit.
No arrests have been made.
A statement on the Tottenham website said: "Carlo Cudicini has fractured his wrists and injured his pelvis after being involved in a road accident this morning.
"The 36-year-old Italian goalkeeper has been admitted to hospital and undergone scans under the supervision of club medical staff.
"The club will update supporters on Carlo as soon as there is any further information."