Harry Redknapp is relishing the chance to play the Barclays Premier League heavyweights as Tottenham continue their battle against relegation.
Spurs meet fourth-placed Aston Villa on Saturday with matches against Chelsea, Manchester United and Everton to come as the season reaches its finale.
Redknapp thinks this is the best time of the season to play the top clubs whose busy fixture schedule includes domestic and European Cup ties.
He said: 'You want to play the big clubs towards the end of the season as they are involved in the Champions League and FA Cup semi-finals.
'It happened to me at Portsmouth when we played Arsenal. They had a Champions League match before and after. Three or four of their best players didn't play against us. It is all part of the luck of the draw.'
Liverpool beat Real Madrid 1-0 away and then lost 2-0 at Middlesbrough in their next game.
'It's about catching teams right,' said Redknapp. 'It was a nice time to play Liverpool on Saturday after Real Madrid. I said to a lot of people that I could not see Middlesbrough getting beaten by Liverpool.'
Redknapp is also heartened by Tottenham's record against the established Big Four of the Barclays Premier League.
He said: 'If you take away the cups, we haven't lost to a top-four team this season.
'As far as I'm concerned, Manchester United didn't beat us at Wembley the other week either - that was a draw.
'They are all hard games but we can beat anyone on our day.'