Saturday's victory against Sheffield United came at a cost as Nathan Dyer and Jordi Lopez were sent off for two bookable offences and will serve one-match bans.
Ferrie Bodde will also miss the clash after injuring his knee after just nine minutes of his first start since November against the Blades. The Swans are awaiting the results of a scan but he will definitely not feature against Rovers.
Joe Allen was ruled out of the 2-1 win against Kevin Blackwell's side after suffering a recurrence of a hamstring injury, and he could be out for three weeks.
Fellow midfielder Leon Britton is also doubtful with a toe injury that ruled him out at the weekend.
Andrea Orlandi (thigh), Fede Bessone (groin), Albert Serran (ankle) and Guillem Bauza (knee) are also sidelined while Cedric van der Gun (thigh) faces a fitness test. On a positive note, Darren Pratley (shoulder) is back in training and Marcos Painter (calf) is available for selection.