Victor Moses is likely to be out for three months after dislocating his shoulder in the Carling Cup loss to Arsenal on Tuesday.
Pressure: Boselli (right) is yet to justify his £6.5million price tag
Hugo Rodallega is still suspended and Franco di Santo (ankle) is rated 50-50, but manager Roberto Martinez is at least hopeful Mauro Boselli (knee) will be fit.
Club captain Gary Caldwell (thigh) could be fit but fellow defender Emmerson Boyce (hamstring) is unlikely to feature despite making good progress.
Team (from): Al Habsi, Alcaraz, Gohouri, Stam, Figueroa, N'Zogbia, Diame, Cleverley, Gomez, Thomas, Boselli, S Caldwell, Watson, Di Santo, G Caldwell, McArthur, McManaman, Mustoe, Pollitt.
CLICK HERE FOR THE WEEKEND TEAM NEWS IN THE BARCLAYS PREMIER LEAGUE Explore more:People: Emmerson Boyce, Gary Caldwell, Roberto Martinez, Victor Moses