Jordi Alba has been withdrawn from the Spain squad for Sunday's World Cup qualifier against Albania after suffering a thigh strain in the draw with Italy.
The Barcelona left-back was replaced after 22 minutes of the first half on Thursday, as Spain drew 1-1 in Turin.
Now the 27-year-old will head back to his club for treatment.
A statement on the Spain squad's website said: "Jordi Alba, international from FC Barcelona, will this morning leave the camp and return to Spain, after confirmation following medical tests that he has suffered a low-grade muscle injury in the back of his left thigh.
"The player came off in the 22nd minute of the Italy-Spain match and his definitive diagnosis was pending the tests that have been carried out this morning.
"The medical staff of the RFEF (Spanish football association) have contacted their colleagues at FC Barcelona to inform them about the diagnosis."
Alba was carried off, to be replaced by Real Madrid's Nacho, who may start the weekend match.
Albania have started their campaign with wins against FYR Macedonia and Liechtenstein to make the early running as leaders of Group G.
Source: PA
