Laurent is needed in attack after the sale of top-scorer Lee Barnard, as he is the current leading scorer with three league goals.
Manager Steve Tilson will also be without key midfielder Alan McCormack.
The former Preston man begins a two-match suspension after he collected his 10th booking of the season against Millwall.
On-loan Sunderland defender Jean-Yves M'Voto is still continuing his rehabilitation from hip surgery and remains a doubt.
Tilson is looking for a first win in four to stop the Shrimpers from sliding down the League One table.