Southampton head coach Jan Poortvliet has left the club to be replaced by fellow Dutchman Mark Wotte.
Poortvliet only took charge at St Mary's in the summer, but has seen his side struggle to keep away from relegation danger in the Championship, with the Saints currently one but bottom.
A statement on the club's official website confirmed: "Following discussions with Southampton Football Club, Jan Poortvliet has stepped down from his role as head coach with immediate effect.
"Poortvliet has taken the decision to stand down from his position in response to the club's poor home form.
"Mark Wotte has been asked by the board to take over as head coach and he will take charge of the team for Tuesday's trip to Norwich City."
Saints chairman Michael Wilde added: "It is a great pity but home results have led to Jan's decision to stand down. He has made a great contribution to the club and the development of individual players.
"Jan is a man of the utmost honesty and integrity. However, professional sport is all about results and we all sink or swim by reference to the scoreboard.
"We embarked on this season with a very young squad of players, many of who have flourished as individuals under Jan's guidance. Sadly, team performance and overall results have not.
"Jan has recognised this and has decided that the club is best served if he stands down."