Southampton duo Dejan Lovren and Calum Chambers are expected to be announced as Liverpool and Arsenal players respectively on Monday.
The summer of change at St Mary's continues apace, with manager Mauricio Pochettino's exit to Tottenham compounded by the departure of a number of key players.
Left-back Luke Shaw became the most expensive teenager of all time in his move to Manchester United, while Adam Lallana followed Rickie Lambert in moving to Liverpool.
They are now set to be joined at Anfield by Croatia international Lovren, who is expected to be announced as a Liverpool player on Monday.
The outspoken 25-year-old has made no secret of his desire to leave the club he joined from Lyon last summer, moving for a deal Press Association Sport understands to be worth Â£20million.
Chambers' exit has come as more of a surprise, although Arsenal have clearly seen enough from the versatile right-back to make their move.
It is understood a deal should be announced on Monday as Arsene Wenger adds a third Saints academy graduate to his squad, having previously signed Theo Walcott and Alex Oxlade-Chamberlain.