New Southampton boss Nigel Adkins will be without Lee Barnard and Adam Lallana for the trip to MK Dons.
Striker Barnard misses out as he serves the final instalment of a three-match ban for his sending-off against Swindon in the Johnstone's Paint Trophy.
Midfielder Lallana faces around six weeks on the sidelines after undergoing an operation on his injured knee and will not be back until the end of October.
Summer signing Frazer Richardson is still recovering from a dislocated shoulder but hopes to finally make his debut some time next month.
Fellow injury victims Dan Seaborne (foot) and Lee Holmes (groin) remain doubtful.
Adkins will be hoping to inspire a change in fortunes, with Saints having lost all three games since former boss Alan Pardew was sacked last month.