Scunthorpe travel to Burnley without on-loan striker Freddie Sears after he was recalled by parent club West Ham last week.
Sears had been expected to stay at Glanford Park until January 3 but Hammers manager Avram Grant opted to terminate the 21-year-old's loan in the hope he can add some firepower to his own squad.
However, defender David Mirfin will return from a foot injury while Josh Wright, Michael O'Connor and Chris Dagnall have shaken off viruses.
They would have been available to face Preston on Boxing Day had the game not been postponed.
Defensive trio Michael Raynes (thigh), Jim McNulty (ankle) and Niall Canavan (knee) are set to remain sidelined while Jonathan Forte should come in for Sears as the Iron seek to avoid a sixth straight defeat.