Scunthorpe boss Ian Baraclough will be without striker Joe Garner for the home clash with high-fliers Nottingham Forest.
Garner is on loan at Glanford Park from Forest and is ineligible to face Billy Davies` men under the terms of the deal.
Garry Thompson will also be missing after he underwent groin surgery last week but Chris Dagnall, Rob Jones and David Mirfin could return to Baraclough's plans.
The Iron have won only once at Glanford Park this season and that victory came back in August.
They now face three successive home games against Forest, Derby and Sheffield United.
"We've got three games coming up at home now which will shape our season," said Baraclough.