Scotland travelled to Macedonia without Jordan Rhodes and Charlie Adam.
The Scottish Football Association announced on its Twitter feed that the pair were out of the squad for the World Cup Group A match on Tuesday night.
Rhodes came on as a substitute for Leigh Griffiths midway through the second half of Scotland's 2-0 defeat by Belgium on Friday night while Adam was an unused substitute.
Manager Gordon Strachan also has Nottingham Forest forward Jamie Mackie and Leeds striker Ross McCormack to call on for the match in Skopje.
Source: PA
