Rotherham boss Ronnie Moore will be without Callum Kennedy and Ryan Taylor for the home clash with Accrington.
Defender Kennedy, on-loan from Swindon, will complete a one-match ban following his debut sending-off in Saturday's 2-1 defeat at Oxford.
The 21-year-old was handed a straight red card for a professional foul after 64 minutes when he hauled down Steven MacLean inside the box.
Winger Ryan Taylor suffered a groin strain after 15 minutes of the game and is a major doubt to face Stanley.
Tom Newey and Omar Daley, who would be making his first start for the club, are expected to replace the duo.
Defender Ryan Cresswell is making good progress following his broken collarbone but is still a few weeks away from returning to action.