Oxford have no fresh injury concerns ahead of the trip to Greater Manchester.
James Henry started the win over Doncaster having overcome a knee complaint while Joe Rothwell was fit enough to come off the bench following a hamstring problem.
Ivo Pekalski remains sidelined as the summer signing works his way back from a serious knee injury.
Other than that, manager Pep Clotet has a strong squad to choose from as the U's go in search of a third league win since mid-October.
Rochdale striker Steven Davies will be looking for a place in Keith Hill's starting line-up after his efforts at Bradford last weekend.
Davies returned from almost a month out to come off the bench to score his side's third goal in their 4-3 defeat at Bradford.
It was his fifth goal of the season and made it 3-3. but Bradford secured the points with a Tyrell Robinson winner 12 minutes from time.
Keith Keane is closing in on a return to full fitness and could be considered for this game.