Derby midfielder Jeff Hendrick will make his first start for the Republic of Ireland in their friendly against Spain in New York.
The 21-year-old will line up alongside James McCarthy in a youthful partnership in a team featuring seven changes from the one which started against the Faroe Islands in Dublin last Friday evening.
Sean St Ledger and skipper Robbie Keane are the only survivors from the Euro 2012 clash between the two countries, which the Spaniards won 4-0 in Gdansk on June 14 last year.
Ireland team: David Forde; Paul McShane, Sean St Ledger, Darren O'Dea, Stephen Kelly; Seamus Coleman, Jeff Hendrick, James McCarthy, Andy Keogh; Robbie Keane (Capt.), Conor Sammon.