QPR defender Clint Hill is to undergo an operation on a long-standing ankle injury.
The left-back was rested for Saturday's 2-0 victory at Watford and is also set to miss next weekend's Championship finale at home to Leeds.
"Clint has played 43 games this season but if you saw the bits floating around in his ankle on the X-ray you wouldn't know how he had played 20 games," said boss Neil Warnock.
"He'll have to have an operation."
Goalkeeper Paddy Kenny and centre-half Fitz Hall could also miss the Leeds match.
Kenny suffered a recurrence of a shoulder injury in the warm-up at Vicarage Road and Hall hurt his hamstring in the first half.