Preston boss Darren Ferguson will be without Iain Hume for the visit of Barnsley to Deepdale.
The striker, who netted his third goal for North End in Saturday's 1-1 draw at Bristol City, is on loan from Barnsley and thus ineligible to face his parent club.
Hume's absence could signal a return for youngster Adam Barton but Ferguson will check on the fitness of defender Wayne Brown, who has been suffering with chickenpox.
The centre-back was still able to take his place among the substitutes at the weekend but Craig Morgan may be asked to continue alongside Sean St Ledger again.
Ferguson said: "Obviously he isn't infected now but I'm just trying to put bodies on the bench - we could do with getting more bodies in."