Gary Roberts could return for Pompey
Portsmouth could bring midfielder Gary Roberts back into the side for the visit of Luton.
Roberts has been rested for the last two matches, with manager Paul Cook keeping faith with the same starting XI.
Striker Jamal Lowe is set to join up with Pompey following his move from Vanarama National League South side Hampton & Richmond, but may not yet feature.
Forward Curtis Main remains sidelined with an abdominal problem.
Luton boss boss Nathan Jones made four changes for the 3-1 win over Barnet on New Year's Eve.
However, full-back Dan Potts went off during the first half with a knee problem, so will be assessed with Alex Gilliead on standby to come into the defence.
Forward Jordan Cook, midfielder Jonathan Smith and defender Alan Sheehan will all be hoping to retain their places in the side.
The Hatters will be again be without midfielders Danny Green (leg) and Nathan Doyle (Achilles).