Steve Cotterill's men have made a miserable start to the season and picked up just one point in their opening four league games.
They are currently bottom of the table, but Hughes has urged Pompey to raise their game ahead of the clash with Ipswich on September 11.
Hughes said: "They are all tough games. We were in no doubt at the start of the season that there would be no easy games in this league.
"Everyone rolls their sleeves up and gives 100% - we'll expect nothing less when Ipswich come to Fratton Park. We'll have to work hard and play to the best of our ability if we want to get the three points."