Portsmouth's FA Cup hopes have been hit by the news defender Hermann Hreidarsson and striker Danny Webber face at least six months on the sidelines.
A scan revealed Webber suffered a ruptured anterior cruciate ligament in Saturday's 2-0 defeat at Tottenham. The striker will see a specialist in London next week ahead of surgery.
Hreidarsson ruptured an Achilles in the same game and will have surgery in London next week.
The news is a blow for Pompey ahead of the April 11 FA Cup semi-final against Spurs at Wembley, as they seek some solace from a desperate season.
The club are on the brink of relegation from the Barclays Premier League having had nine points docked from their total after entering administration.
It was the last news manager Avram Grant wanted, given the likes of David James, Marc Wilson, Nadir Belhadj, Papa Bouba Diop, Kevin-Prince Boateng, Tal Ben-Haim and Hassan Yebda are also fighting for fitness.
Jamie O'Hara is also unlikely to be available for the cup tie under the terms of his loan deal from Spurs, while Aruna Dindane is unavailable because another appearance will trigger a payment to Lens which the cash-strapped club simply cannot afford.
Portsmouth's head physio Gary Sadler told his club's official website, www.portsmouthfc.co.uk: "Hermann's Achilles just went, while Danny went to move and felt his knee shift. It's devastating for both of them."