The Football League have confirmed Plymouth have been deducted 10 points with immediate effect.
The confirmation comes via a statement on the Football League's official website after the Pilgrims issued a 'Notice of Intention' to appoint an administrator.
The statement read: "The Football League can confirm that Plymouth Argyle Football Club have been deducted 10 points with immediate effect."
It continued: "This sporting sanction has been implemented following receipt of formal confirmation that the club had filed a notice of intention to appoint an administrator with the High Court."
The League One club have faced winding-up orders this season and it was revealed last week that players and staff have still not been paid their wages for January.
Manager Peter Reid said: "We are going to have to produce Championship form to stay up. It's going to be a battle, I don't mind a battle. There are people worse off than us, we have to get on with it."