Plymouth are monitoring the fitness of skipper Carl Fletcher ahead of their game against Colchester.
The former West Ham midfielder missed last Saturday's defeat against Peterborough with a thigh problem and although he returned to training earlier this week, the Welshman is not certain to be fit.
Central defender Kari Arnason returns after serving a one-match ban following his sending-off at Walsall and is expected to be in the starting line-up.
But midfielder Luke Summerfield will play no part due to a knee problem and New Zealand striker Rory Fallon will be sidelined for the rest of the month after undergoing a hernia operation.
Argyle winger Yannick Bolaise is also expected to miss out once again as he continues his recovery from an ankle operation.