Plymouth boss Peter Reid will have Yala Bolasie back in his squad for the home clash against Colchester.
The pacy winger has missed the last three games following his sending-off against Yeovil on February 1 due to an off-the-ball incident, but is likely to go straight back into the starting line-up against the Us.
Teenage midfielder Luke Young, who made his debut for the club during Tuesday night's 4-0 defeat at Brighton on his 18th birthday, could drop to the bench.
Karl Duguid and Rory Fallon will both be hoping for recalls following their substitute appearances in midweek, and Duguid could replace Kari Arnason, who is now just one booking away from a two-match ban.
Defender Onismor Bhasera is continuing his rehabilitation from a knee problem and is unlikely to be involved as the Pilgrims look to end a run of six successive league defeats.