While the thumping hangover following Paris Saint-Germain's Champions League exit in midweek still lingers, the capital club might be able to sooth the pain by securing the Ligue 1 title on Sunday.
Laurent Blanc's expensively-assembled squad were within minutes of the semi-final spot they so badly craved at Chelsea's Stamford Bridge before a late Demba Ba strike took the Londoners through on away goals and plunged PSG into depression.
They must now turn their attentions to putting the finishing touches on an almost perfect domestic campaign, and they stand on the brink of a fourth French title as they travel to Lyon on Sunday night.
Nearest challengers Monaco sit 13 points adrift in second place with six games to go, and if they lose away to Rennes on Saturday, the path will be clear for PSG to win a second straight championship by beating Lyon at the Stade de Gerland, the same venue where they wrapped up the title last year.
The match against Remi Garde's fifth-placed Lyon side will also serve as a rehearsal for the League Cup final between the two teams at the Stade de France on Saturday, April 19.
Blanc's reported contract extension past 2015 appeared a formality before the derailment in London but with the club's Qatari owners craving Champions League success, reports this week suggest that he could yet be axed.
The coach and his squad have been hit badly by the end of their European adventure and training was cancelled the day after the match as the club got to grips with their defeat.
Uruguayan striker Edinson Cavani was targeted as one of the players to underperform on the biggest stage and much has been said of their lack of experience needed to win Europe's biggest competition.
"Difficult to accept a result like that," Cavani tweeted after the match.
"We now have to concentrate on our other objectives."
They will be facing a Lyon side who were also eliminated from Europe this week, losing 2-1 away to Juventus in the second leg of their Europa League quarter-final tie to bow out 3-1 on aggregate.
- Anigo 'got it wrong' -
Monaco coach Claudio Ranieri will be keen to maintain their six-point lead over third-placed Lille while Saint-Etienne in fourth must win at Reims to keep their slim hopes of qualifying for next season's Champions League alive.
Les Verts faltered badly last week when they were held to a 1-1 home draw by Nice and a five-point deficit to Lille needs to be reduced quickly if they hope to return to the European Cup for the first time since 1981.
Lille entertain relegation-threatened Valenciennes in a local derby in Saturday's early match.
Meanwhile, Marseille make the short trip to Montpellier on Friday and coach Jose Anigo admitted this week he may have made a mistake in taking the job back in December after coming in for a torrent of abuse last weekend during the 3-1 home win against Ajaccio.
Anigo, who will return to his primary role of sporting director in the summer, has endured a difficult time since the murder of his son Adrien back in September.
"There has been a form of disrespect and forgetfulness from the fans, so yes you can ask the question," he replied when asked whether he regretted taking the job when Elie Baup was sacked.
"Did I make the right decision to offer my services to the club because I got nothing in return and I didn't make more money?
"I possibly got it wrong but I am curious to see how it's going to finish for me."
Elsewhere, Ajaccio will be relegated on Saturday if they lose at home to Bordeaux.
Fixtures (all kick-offs 1800GMT unless stated)
Montpellier v Marseille (1830GMT)
Lille v Valenciennes (1500GMT), AC Ajaccio v Bordeaux, Evian v Bastia, Nice v Lorient, Rennes v Monaco, Sochaux v Toulouse
Nantes v Guingamp (1200GMT), Reims v Saint-Etienne (1500GMT), Lyon v Paris Saint-Germain (1900GMT)