Tottenham Hotspur have confirmed that they will be without five first team players for the visit of Huddersfield Town this Saturday lunchtime, with Dele Alli also a major doubt.
Also being monitored by Spurs physios is Kane's international teammate Alli, who broke his hand against City.
With the second leg against Pep Guardiola's side coming up straight away next Wednesday there is a good chance that, even if he is passed fit, Pochettino may choose to rest Alli to make sure he is fully fit for the game at the Etihad Stadium.
TEAM NEWS:— Tottenham Hotspur (@SpursOfficial) April 12, 2019
@ericdier (hip flexor)
All three players are continuing on-field rehabilitation and remain unavailable.#PL ⚪️ #COYS pic.twitter.com/qj1mshpFEX
This may mean the 47-year-old is able to play a couple of the club's academy prospects such as Kyle Walker-Peters or Oliver Skipp, enabling his first team regulars to have a break but still having a side strong enough to pick up the three points, which are vital in the race for the top four.