The Dutchman will continue in goal with Steve Harper providing the back-up following Fraser Forster's departure on loan for Celtic, while Ameobi, who has six derby goals to his name to date, will also be retained.
Hold on: Ameobi (left) will keep his place for the derby
Ryan Taylor is again likely to start at left-back with Jose Enrique's replacement yet to arrive, while summer signing Sylvain Marveaux and Shane Ferguson (ankle) could be involved after building up match fitness in a practice game in midweek, but Hatem Ben Arfa (ankle) remains on the sidelines.
Provisional squad: Krul, Harper, Simpson, R. Taylor, Ferguson, Coloccini, S. Taylor, Williamson, Tiote, Cabaye, Gutierrez, Barton, Marveaux, Obertan, Gosling, Abeid, Ba, Shola Ameobi, Lovenkrands, Best, Vuckic, Sammy Ameobi.
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