Fans have reacted angrily to the 22-year-old's departure for Anfield during the final hours of the January transfer window, with some blaming the club for allowing him to leave and others venting their fury on the player for turning his back on the Magpies.
Pardew, whose side host Arsenal on Saturday, said: "Unfortunately, it's one of those things that isn't going to go away for a long period, I shouldn't think.
"We have to deal with that and we have to cope with that. It's not about one player, of course, it's about Newcastle United and we have to be resilient, be strong in our minds that it isn't going to affect us. If we start thinking it will, then it most certainly is going to.
"But I just feel the emphasis of the team and the group is strong towards the club, and you will see that in the performance they put out. I have no doubt that we will do everything we can to try to beat a very, very good Arsenal team."