Like forward Gouffran, Debuchy was ineligible for Thursday's 3-1 Europa League defeat at Benfica, but he has also been nursing a hamstring problem and Pardew is unsure whether or not the defender, or midfielder Tiote (hamstring), will be fit enough to feature this weekend.
The manager does not expect Massadio Haidara (knee) to be ready to make his return to action against the Cottagers and has ruled out Fabricio Coloccini (back) doing so, while fellow defender Danny Simpson says he should be fit to play despite suffering a knock to the ankle in the Benfica match.
Fulham midfielder Steve Sidwell is suspended following his sending-off against QPR on Monday night.
Midfielder Ashkan Dejagah is out for a week with a sprained ankle while striker Mladen Petric is unavailable because of an adductor problem.
Midfielder Mahamadou Diarra is out for the rest of the season with a knee injury.
Newcastle (from): Krul, Elliot, Santon, Simpson, Williamson, S Taylor, Yanga-Mbiwa, Perch, Debuchy, Bigirimana, Cabaye, Anita, Gutierrez, Gosling, Marveaux, Obertan, Sissoko, Tiote, Cisse, Gouffran, Ameobi, Campbell.
Fulham (from): Schwarzer, Somogyi, Etheridge, Riether, Hangeland, Hughes, Senderos, Riise, Baird, Karagounis, Kacaniklic, Frimpong, Davies, Richardson, Frei, Mesca, Enoh, Berbatov, Duff, Ruiz, Emanuelson, Rodallega.
Source: Newcastle United Mad