Clark had to serve a two-match ban for incurring 10 bookings this season and was ruled out of the home defeat by Wolves and the draw at Everton.
Full strength: Clark is set to go back into the squad
Villa boss Gerard Houllier has a full strength squad to choose from as his players look to avenge a 6-0 defeat at St James' Park earlier in the campaign.
Houllier has to decide whether to persevere with the 4-4-2 system he switched to against Everton or revert to operating with record signing Darren Bent as the sole striker.
Villa (provisional squad): Friedel, Walker, Collins, Dunne, Luke Young, Downing, Reo-Coker, Makoun, Ashley Young, Agbonlahor, Bent, Marshall, Clark, Heskey, Pires, Albrighton, Delph, Petrov, Cuellar.
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Explore more:People: Darren Bent, Gerard Houllier, Ashley Young, Luke Young Places: Newcastle