MK Dons could have three new players in their squad for the visit of Oxford.
Robbie Neilson's squad was bolstered by the deadline-day additions of defender Scott Golbourne, midfielder Alex Gilbey and winger Aidan Nesbitt.
Neilson will assess his injured players on Friday, with Osman Sow, Joe Walsh, Kieran Agard and Chuks Aneke all missing the league defeat at Blackburn while Peter Pawlett and Callum Brittain were absent in the EFL Trophy in midweek.
Robbie Muirhead and Paul Downing could be in line for recalls should Neilson want to make changes after the heavy loss at Ewood Park.
Oxford could hand debuts to deadline-day signings John Mousinho and Alex Mowatt.
Marvin Johnson left the club on Thursday, moving to Championship Middlesbrough for an undisclosed fee.
Elsewhere, Oxford hope to have Brazilian left-back Ricardinho available after he bruised his back in last Saturday while skipper Curtis Nelson is expected to be involved after missing the Checkatrade Trophy rout of Stevenage.
Midfielder Ivo Pekalski (knee) and defenders Charlie Raglan (ankle) and Sam Long (knee) remain out.