Roberto Di Matteo's stuttering side travel to in-form Leeds in need of a victory to re-ignite their bid for automation promotion after failing to win in their last three games.
Leeds, in contrast, have won five and drawn two of their last seven League One games to move up to fifth, four points behind the fourth-placed Dons.
Howell told the club's official website: "All the boys are looking forward to it, everyone's desperate to play, it's a great stadium and the atmosphere is going to be unbelievable.
"After Tuesday's result (a 2-2 draw against Crewe) we'll definitely be up for it. We always seem to play well against the big teams, we dominated Leicester here, so maybe this is just the kind of game we need.
"We won 3-1 against Leeds here in what I think was one of our best performances of the season so it will give us a lot of confidence. But obviously they're going to remember that so they're going to come at us on Saturday."