MK Dons will be without striker Sam Baldock for the trip to face Leyton Orient.
Baldock made his return from a hamstring injury as a substitute at Dagenham & Redbridge on Saturday but lasted just 15 minutes before hobbling off again to leave manager Karl Robinson frustrated.
Robinson said: "It's not yet clear how long he's going to be out but he won't travel to Orient in midweek."
Defender Gary Mackenzie missed out at the weekend with a head injury but could be fit enough to return while Mat Doumbe came through the full 90 minutes at Dagenham after a head injury of his own.
On-loan QPR striker Angelo Balanta will be out of action until March with an ankle problem while fellow Rangers forward Rowan Vine will again be on the bench after joining the club last week.